Diagnosis and management offers comprehensive coverage of all aspects of this topic. Salivary gland tumors free download as powerpoint presentation. The major and minor salivary glands give rise to a variety of both benign and malignant. Signs of salivary gland cancer include a lump or trouble swallowing. The most common malignant minor salivary gland tumors are adenoid cystic 32%69%. The world health organization lists several benign salivary gland tumors. Salivary glands tumors are uncommon and are subdivided into benign. Here, we report a case of a 55yearold male patient with massive bcac of palatal minor salivary gland extending into the maxillary sinus. Salivary gland tumors msd manual professional edition. Salivary gland tumors symptoms and causes mayo clinic. Multiple tumors of the major salivary glands the american. Radiotherapy if a salivary gland tumour is cancerous, radiation therapy may be necessary fast neutron therapy has been used successfully to treat salivary gland tumors, 11 and has shown to be significantly more effective than photons in studies treating unresectable salivary gland tumors.
Beginning with the embryology, anatomy and physiology of the salivary glands, the first section of the book discusses radiographic imaging, infections, cystic conditions, sialoadenitis and sialolithiasis, and systemic diseases. Detailed information is presented on molecular characterization and radiological staging, and a series of treatmentrelated chapters describe the different surgical approaches to major and minor salivary gland cancer, including reconstructive surgery techniques, and the roles of radiotherapy and heavy. Seroustype acini of a parotid gland with dense secretory granules histologic section of a submaxillary gland. Another important feature to incorporate is the newly gained knowledge about genetics in salivary gland tumors, a knowledge that has emerged during the last 34 years.
Being exposed to certain types of radiation may increase the risk of salivary cancer. Minor salivary glands msg are numerous 700 to 900 exocrine glands, which are distributed in the submucosa of the oral cavity, nasopharynx, tonsils, hypopharynx, and larynx. Acinic cell carcinoma 3% of all salivary gland neoplasm 8090% in parotid 15% of all parotid tumors mean age is 4050 years 23 occur in female 3% shows bilateral involvement second most common salivary gland tumor in children well circumscribed tumor with fibrosis tissue macroscopically. Salivary gland carcinomas sgcs are rare, accounting for salivary gland tumours is a major challenge for radiologists due to the great variety of differential diagnoses. Benign tumors represent over 80% of all salivary gland tumors of the lip. Inflammatory tumors and benign cysts represent the major cause of salivary gland enlargements in children. The three main pairs of salivary glands are the parotid glands, the sublingual glands, and the submandibular glands.
Bcac involving palatal minor salivary glands are exceedingly rare, and only 10 cases have been reported in the literature. There are several pairs of salivary glands in different locations a major pair in front of the ears parotid glands. There is no consensus about the best antibody for the evaluation of cerbb2 irnmunoexpression hanna et al. Minor glands hundreds residing in the oral cavity, pharynx and paranasal sinuses major salivary glands parotid gland borders superior zygomatic arch. Characterization ie, benign or malignant, and histological type, location deep or superficial. Patients range in age from 9 to 84 years with a slight female predominance. Current concepts in diagnosis of unusual salivary gland tumors. Newlands, md, phd 62602 salivary gland neoplasms benign neoplasms malignant neoplasms controversial issues. These disease entities are relatively rare, histologically diverse, and may involve several anatomically distinct sites. Ppt salivary gland tumors powerpoint presentation free to download id. There are also hundreds of small minor salivary glands lining parts of the mouth, nose, and larynx that can be seen only with a microscope.
Pembrolizumab for the treatment of advanced salivary gland. Salivary gland pathology book also available for read online, mobi, docx and mobile and kindle reading. An approach to the why is salivary gland pathology. The majority of salivary gland tumors occur in the parotid glands. Ppt salivary gland tumors powerpoint presentation free to. Ppt salivary gland tumors powerpoint presentation free. The submandibular glands are smaller and are below the jaw. Salivary gland tumours are rare and most cases are referred to the head and neck clinic. The incidence of benign to malignant tumors of the lip does not follow the inverse relationship stated in the axiom that the smaller the salivary gland the greater the probability that a developing tumor will be malignant.
The annual incidence of salivary gland cancers ranges from 0. Salivary gland tumors are abnormal cells growing in the ducts that drain the salivary glands. Salivary gland tumors tehran university of medical sciences. In case of a tumor, hemangioma is the most common histotype within the salivary glands in these patients baker and malone 1985. Most small salivary gland tumors begin in the palate roof of the mouth.
Pdf download salivary gland pathology free unquote books. This article gives a short overview on the anatomy of the salivary glands, the epidemiology of salivary gland tumours as well as the clinical presentation and the different imaging modalities including new magnetic resonance techniques such as diffusionweighted magnetic. Each gland has its own tube duct leading from the gland to the mouth. Definition a salivary gland tumor is an uncontrolled growth of cells that originates in one of the many salivaproducing glands in the mouth. Oct 26, 2018 you have three pairs of major salivary glands parotid, sublingual and submandibular. Pleomorphic adenoma is the most common parotid gland tumor and superficial parotidectomy with preservation of the facial. Salivary gland tumors information mount sinai new york. Salivary gland tumors sgts are usually in the parotid uncommon 5. Salivary gland tumors of the lip jama otolaryngology. Salivary gland tumors definition of salivary gland. Neoplasms of the salivary glands in a turkish adult population. Salivary gland tumors ppt by dr gulzar a bhat authorstream. Salivary gland cancer is a rare disease in which malignant cancer cells form in the tissues of the salivary glands. Portion of a parotid gland demonstrating multiple foci of sebaceous differentiation.
Initially treated as one single disease, its diagnosis, prognosis, and treatment are currently being stratified based on morphology. The majority of these neoplasms are benign and only 20% are malignant. The major and minor salivary glands give rise to a variety of both benign and malignant lesions. Salivary gland tumors can begin in any of the salivary glands in your mouth, neck or throat. Salivary gland tumors are abnormal cells growing in the gland or in the tubes ducts that drain the salivary glands. Salivary gland tumors are rare types of tumors that begin in the salivary glands.
Multidisciplinary management of salivary gland cancers. This article is from journal of dental research, dental clinics, dental prospects, volume 4. Malignant minor salivary gland tumors of the larynx. Salivary gland tumors of the lip jama otolaryngologyhead. A total of 125 primary salivary gland neoplasms, consisting of. For malignant tumors, treatment is with excision and radiation.
Tests that examine the head, neck, and the inside of the mouth are. Salivary gland neoplasm an overview sciencedirect topics. Salivary gland tumors an update american society for. Immunohistochemical study of cerbb2 oncoprotein overexpression in human major salivary gland carcinoma. Differentiation of benign and malignant tumors is not the primary goal of ct and mri. J w keyes, jr, b a harkness, k m greven, d w williams, 3rd, n e watson, jr, w f mcguirt. Description the tongue, cheeks, and palate the hard and soft areas at the roof of the mouth contain many glands that produce saliva. Download pdf genuine tumor manual huang xiaochinese. High grade tumors, on the other hand, seem to arise more often in major salivary glands kokemueller et al. Ppt salivary gland neoplasms powerpoint presentation. About 10% to 20% of salivary gland tumors start in these glands, and about half of these tumors are cancerous. Acinic cell carcinoma 3% of all salivary gland neoplasm 8090% in parotid 15% of all parotid tumors mean age is 4050 years 23 occur in female 3% shows bilateral involvement second most common salivary gland tumor in children well circumscribed tumor. Sep 12, 2015 the parotid gland is the largest of the major salivary glands and the commonest site for salivary tumors, the majority of which are benign. Tumors of the parotid gland salivary gland pathology.
Minor salivary gland tumors are most commonly located in the oral cavity, particularly the hard palate, and less commonly in the nasal cavity, paranasal sinuses, pharynx, and larynx. Salivary gland tumors tumors that arise from the salivary gland may arise from the salivary epithelium the parenchyma or the supportive stroma mesenchymal benign parenchymal tumors are known as adenomas malignant tumors are known as adenocarcinomas. Salivary gland tumors are relatively uncommon and account for approximately 36% of all neoplasms of the head and neck. Worldwide, the annual incidence of tumors of salivary gland origin represents more than 0. Newly described salivary gland tumors modern pathology. Patients with multiple salivary gland tumors are uncommonly seen and infrequently re ported on 1d. Salivary gland tumors definition of salivary gland tumors. However most cancerous malignant salivary gland tumors start in the parotid glands. A free powerpoint ppt presentation displayed as a flash slide show on id. Posterior angle of mandible under earlobe toward the mastoid tip. Anatomy major glands parotid, submandibular and sublingual glands. Neoplastic disorders of salivary glands are in general relatively rare and account for 3 to 6% of head and neck tumors.
A painless salivary mass is the most common sign and is evaluated by fineneedle aspiration biopsy. Download salivary gland pathology in pdf and epub formats for free. Salivary gland tumors merck manuals professional edition. The salivary gland cancers account for approximately 6% percent of neoplasms of head and neck cancers stenner and klussmann, 2009.
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